I am running http://osc.lv/ and http://portfolio.konstruktors.com/ on Nginx + PHP (with FPM patch) and APC for object cache.
The performance is phenomenal: 6 queries in 0.045 seconds. Pingdom Tools is reporting 0.6 second load time for the whole page (which is faster than Google's home page)!
The "problem" (or rather a feature) of Nginx is that it can't have something dynamic like .htaccess. Every time you edit nginx rewrite rules, you have to restart the server (reload the configuration).
So you have extremely low resource requirements for Nginx (which would be perfect for shared hosts) and no support for something like .htaccess.
My idea was to have something like a single master nginx process for every user (with its own config file) with ability to restart/reload only that single process. Don't know if it can be done.
Let me know if anyone would be interested in reading a post about my setup and experimentation.


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